Dysplasia in MSM population

Dysplasia is a synonym for cancer:

 Merriam-Webster's Medical Dictionary

Main Entry: dys·pla·sia
Pronunciation: dis-'plA-zh(E-)&
Function: noun
1 : variation in somatotype (as in degree of ectomorphy, endomorphy, or mesomorphy) from one part of a human body to another
2 : abnormal growth or development (as of organs or cells); broadly : abnormal anatomic structure due to such growth —dys·plas·tic /-'plas-tik/ adjective

 

The prevalence, and predictive value, of abnormal anal cytology to diagnose anal dysplasia in a population of HIV-positive men who have sex with men
Authors: Cranston, R.D.1; Hart, S.D.2; Gornbein, J.A.3; Hirschowitz, S.L.2; Cortina, G.2; Moe, A.A.4
Source: International Journal of STD & AIDS, Volume 18, Number 2, February 2007, pp. 77-80(4)
Courtesy of the:  Royal Society of Medicine Press

Abstract:

Due to the increasing incidence of anal cancer in HIV-positive men who have sex with men, and the potential to detect and treat high-grade anal dysplasia - the putative anal cancer precursor - we have introduced an anal cytology screening service. Patients with abnormal anal cytology have follow-up high-resolution anoscopy (HRA) with biopsy of lesions clinically suspicious for high-grade dysplasia. In total, 244 men were screened and 235 (96%) of the samples were adequate for cytological interpretation using the Bethesda 2001 system. One hundred and sixty-four (67%) men had abnormal anal cytology, and 93 of them had follow-up HRA and anal biopsy. The positive predictive value for any anal cytological abnormality to predict any degree of anal dysplasia was 95.7±2.1%, and for any anal cytological abnormality to predict high-grade anal dysplasia was 55.9±5.1%. Abnormal anal cytology was highly predicative of anal dysplasia on biopsy.

Document Type: Research article

DOI: 10.1258/095646207779949772

Affiliations: 1: Department of General Internal Medicine, University of California, Los Angeles, CA, USA 2: Department of Pathology, University of California, Los Angeles, CA, USA 3: Department of Biomathematics, University of California, Los Angeles, CA, USA 4: Department of Infectious Disease, University of California, Los Angeles, CA, USA

 

Study: HIV-positive Practicing Homosexual Men 9000% More Likely to Develop Anal Cancer
By John-Henry Westen

LOS ANGELES, March 22, 2007 (LifeSiteNews.com) - New research has again shown the grave danger of homosexual sex acts to the human body. The grave health risks associated with such dangerous sexual behaviours is one of the prime reasons why society as a whole should oppose homosexual acts, doctors have told LifeSiteNews.com under condition of anonymity.

A study which appears in the February issue of the International Journal of STD & AIDS, has found that "HIV-positive men who have sex with men are up to 90 times more likely than the general population to develop anal cancer."

The study was based on data from 244 patients at the University of California - Los Angeles (UCLA) CARE clinic who had anal cytology screenings (similar to a pap smear) between February 2002 and December 2004. The UCLA authors of the study are: Ross D. Cranston, Steven.D. Hart , Jeffrey A. Gornbein, Sharon L. Hirschowitz, Galen Cortina, and Ardis.A. Moe.

A Canadian doctor who spoke to LifeSiteNews.com (anonymously for fear of reprisal) about the dangers our homosexual sex acts in 2005 stated: "Anal intercourse causes abrasions of the relatively fragile rectal wall, especially in the receptive partner. The penetration of E.coli, always present in the stool, and other bacteria, viruses and parasites penetrate through such lesions into the deeper body tissues. This leads to the suppression of the immune system of such individuals even if there is no exposure to HIV. The immune suppression increases the risk to develop certain cancers, opportunistic infections, to which otherwise one would be resistant, and other health problems including the risk of premature death."

Information on the health risks of gay sex is available from the Gay and Lesbian Medical Association (GLMA). A survey by members of the GLMA released in August 2002 listed the main health problems affecting homosexual men. According to Christopher E. Harris, MD, GLMA President and Vincent M.B. Silenzio, MD, MPH, there are increased health risks for homosexual men.

The most common health problems in homosexual men are:

1. Increased incidence of infectious diseases
- HIV/AIDS*
- syphilis
- gonorrhea
- chlamydia
- pubic lice
- hepatitis A
- hepatitis B
- hepatitis C
- anal papilloma

2. Increased incidence of cancer especially
- colon/rectal
- prostate
- testicular

3. Increased incidence of eating disorders
- bulimia
- anorexia nervosa
- obesity

4. Increased incidences of other psychological problems
- anxiety
- depression
- suicide

5. Increased incidence of addiction problems especially
- tobacco
- alcohol
- street drugs
- amyl nitrates (poppers)